Journal of neurology, neurosurgery, and psychiatry
The most recent articles from:
J. Neurol. Neurosurg. Psychiatr.
-
J. Neurol. Neurosurg. Psychiatr. · Sep 2015
Chronological changes of 123I-MIBG myocardial scintigraphy and clinical features of Parkinson's disease.
The aim of this study was to investigate chronological changes of (123)I-meta-iodobenzylguanidine (MIBG) myocardial scintigraphy and its relation to clinical features in patients with Parkinson's disease (PD), and to characterise patients with PD with normal or mildly low MIBG uptakes at their early stages. ⋯ Follow-up studies of MIBG divided the patients with PD into two major subgroups. A subgroup of patients with PD with normal or mildly low MIBG uptakes at the early stages of illness was characterised by female-dominant, young onset, slow progression in motor dysfunctions and preserved cognitive function.