Journal of neurology, neurosurgery, and psychiatry
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J. Neurol. Neurosurg. Psychiatr. · Apr 2013
Editorial CommentThe neglected role of reward in rehabilitation.
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J. Neurol. Neurosurg. Psychiatr. · Apr 2013
Risk of epilepsy after traumatic brain injury: a retrospective population-based cohort study.
To investigate the associated risk of epilepsy after traumatic brain injury (TBI) in a population-based retrospective cohort study. ⋯ The risk of epilepsy after TBI varied by patient gender, age, latent interval and complexity of TBI. Integrated care for early identification and treatment of post-trauma epilepsy were crucial for TBI patients.
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J. Neurol. Neurosurg. Psychiatr. · Apr 2013
Case ReportsNeurological manifestations of phaeochromocytomas and secretory paragangliomas: a reappraisal.
To determine the frequency and range of neurological manifestations of phaeochromocytomas and secretory paragangliomas. ⋯ Neurological manifestations of phaeochromocytomas and secretory paragangliomas were common, and these tumours can present with various neurological manifestations. The paroxysmal symptoms can be incorrectly attributed to other headache syndromes, panic attacks or cerebral vasculitis. RCVS may play a role in the pathogenesis of the neurological symptoms associated with acute crises and paroxysmal attacks.
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J. Neurol. Neurosurg. Psychiatr. · Apr 2013
Case ReportsJapanese amyotrophic lateral sclerosis patients with GGGGCC hexanucleotide repeat expansion in C9ORF72.
A GGGGCC hexanucleotide repeat expansion in C9ORF72 occurs on a chromosome 9p21 locus that is linked with frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) in white populations. The diseases resulting from this expansion are referred to as 'c9FTD/ALS'. It has been suggested that c9FTD/ALS arose from a single founder. However, the existence of c9FTD/ALS in non-white populations has not been evaluated. ⋯ C9ORF72 repeat expansions were present in a Japanese cohort of ALS patients, but they were rare. Intriguingly, Japanese patients appear to carry the same risk haplotype identified in white populations.