Journal of neurology, neurosurgery, and psychiatry
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J. Neurol. Neurosurg. Psychiatr. · Apr 2012
Non-invasive ventilation in motor neuron disease: an update of current UK practice.
In motor neurone disease (MND), respiratory muscle weakness causes substantial morbidity, and death is usually due to respiratory failure. Non-invasive ventilation (NIV) improves symptoms, quality of life and survival, but previous surveys showed that few patients with MND received NIV. ⋯ Compared with 2000, there has been a marked increase in the number of patients referred for, and currently using, NIV (2.6 and 3.4-fold, respectively). The proportion successfully established on NIV has also increased, suggesting more appropriate selection and/or improvement in the methods of using NIV in this challenging group of patients. However, monitoring of respiratory function is suboptimal and uncontrolled oxygen is sometimes used inappropriately before the terminal phase.
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J. Neurol. Neurosurg. Psychiatr. · Apr 2012
Contactin-associated protein-2 antibodies in non-paraneoplastic cerebellar ataxia.
Relatively few studies have searched for potentially pathogenic antibodies in non-paraneoplastic patients with cerebellar ataxia. ⋯ Prospective studies are now needed to see whether identification of CASPR2 antibodies has relevance for the diagnosis and treatment of idiopathic cerebellar ataxia.
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J. Neurol. Neurosurg. Psychiatr. · Apr 2012
Letter Case ReportsMyasthenia gravis can cause camptocormia.
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J. Neurol. Neurosurg. Psychiatr. · Apr 2012
Biography Historical ArticleNerve fibre degeneration in the brain in amyotrophic lateral sclerosis.