Journal of neurology, neurosurgery, and psychiatry
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J. Neurol. Neurosurg. Psychiatr.
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J. Neurol. Neurosurg. Psychiatr. · Jul 2003
Meta AnalysisHead injury as a risk factor for Alzheimer's disease: the evidence 10 years on; a partial replication.
To determine, using a systematic review of case-control studies, whether head injury is a significant risk factor for Alzheimer's disease. We sought to replicate the findings of the meta-analysis of Mortimer et al (1991). ⋯ This study provides support for an association between a history of previous head injury and the risk of developing Alzheimer's disease.