Journal of neurology, neurosurgery, and psychiatry
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J. Neurol. Neurosurg. Psychiatr. · May 2002
Clinical TrialMagnetic resonance brain imaging in people with dizziness: a comparison with non-dizzy people.
Dizziness is a common symptom affecting about 30% of people over the age of 65. ⋯ Structural abnormalities of the brain and neck are common in both dizzy and non-dizzy subjects. "Routine" MRI is unlikely to reveal a specific cause for dizziness. The observation of more frequent white matter lesions in the midbrain in dizzy subjects requires further study to determine whether small vessel changes could cause dizziness in older people.
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J. Neurol. Neurosurg. Psychiatr. · May 2002
Clinimetric evaluation of a new overall disability scale in immune mediated polyneuropathies.
To determine the validity, reliability, and responsiveness of a new overall disability sum score in immune mediated polyneuropathies. ⋯ All clinimetric requirements were met by the overall (arm and leg) disability sum score in immune mediated polyneuropathies. Its use is therefore suggested in evaluating immune mediated polyneuropathies.
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J. Neurol. Neurosurg. Psychiatr. · Apr 2002
Blood pressure and risk of headache: a prospective study of 22 685 adults in Norway.
Prevalence studies of the association between blood pressure and headache have shown conflicting results. The aim was to analyse the relation between blood pressure and risk of headache in a prospective study. ⋯ In the first prospective study of blood pressure and the risk of headache, high systolic and diastolic pressures were associated with reduced risk of non-migrainous headache. One possible explanation may be the phenomenon of hypertension associated hypalgesia, which probably involves the baroreflex system influencing nociception in the brain stem or spinal cord.
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J. Neurol. Neurosurg. Psychiatr. · Apr 2002
Timing of surgery for supratentorial aneurysmal subarachnoid haemorrhage: report of a prospective study.
The debate on the timing of aneurysm surgery after subarachnoid haemorrhage (SAH) pivots on the balance of the temporal risk for fatal rebleeding versus the risk of surgical morbidity when operating early on an acutely injured brain. By following a strict management protocol for SAH, the hypothesis has been tested that in the modern arena of treatment for aneurysmal SAH the timing of surgery to secure supratentorial aneurysms does not affect surgical outcome. ⋯ The current management of patients presenting with SAH from anterior circulation aneurysms allows early surgery to be followed safely regardless of age. The only independent variables affecting outcome are age and clinical grade at presentation. The timing of surgery did not significantly affect surgical outcome, promoting a policy for early surgery that avoids the known risks of rebleeding and reduces inpatient stay.
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J. Neurol. Neurosurg. Psychiatr. · Apr 2002
Medial temporal lobe atrophy predicts Alzheimer's disease in patients with minor cognitive impairment.
To investigate whether medial temporal lobe atrophy predicted outcome in patients with minor cognitive impairment and whether assessment of the medial temporal lobe could increase the predictive accuracy of age and delayed recall for outcome. Quantitative and qualitative methods of assessing the medial temporal lobe were also compared. ⋯ The ability to detect patients at high risk for Alzheimer type dementia among those with minor cognitive impairment increases when data on age and memory function are combined with measures of medial temporal lobe atrophy. Volumetry of the hippocampus is preferred, but qualitative rating of medial temporal lobe atrophy is a good alternative.