European journal of clinical investigation
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Eur. J. Clin. Invest. · Sep 2013
Portal vein omentin is increased in patients with liver cirrhosis but is not associated with complications of portal hypertension.
Omentin is a visceral fat-derived adipokine associated with endothelium-dependent vasodilation. Impaired endothelial function is a major cause of portal hypertension in liver cirrhosis. The aim was to assess associations of omentin with systemic markers of endothelial function, namely arginine and asymmetric dimethylarginine (ADMA) and complications of portal hypertension in liver cirrhosis. ⋯ Current data show that PVS omentin is increased in liver cirrhosis but is not associated with complications of portal hypertension.