European journal of clinical investigation
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Eur. J. Clin. Invest. · Mar 2024
Assessing the causal association between human blood metabolites and the risk of gout.
The occurrence of gout is closely related to metabolism, but there is still a lack of evidence on the causal role of metabolites in promoting or preventing gout. ⋯ This MR study combining genomics with metabolomics provides a novel insight into the causal role of blood metabolites in the risk of gout, which implies that examination of certain blood metabolites would be a feasible strategy for screening populations with a higher risk of gout.