Lancet
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Comparative Study
Protective effect of rear-seat restraints during car collisions.
The nature of injuries to 2684 car occupants involved in 1055 car accidents were analysed. Less than 1% front-seat occupants were children, compared with 25% of rear-seat passengers. Nearly all (97%) rear-seat passengers were unrestrained. ⋯ Injury severity distribution was similar for front-seat as for rear-seat occupants. Except for minor-to-moderate neck injuries, which were the result of deceleration, most injuries to rear-seat passengers were due to contact with the front seat, with glazing materials, or with other parts of the car. The use of car restraints by rear-seat passengers should reduce the incidence and severity of injuries.
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Serological and clinical data were collected in 348 cases of suspected neonatal alloimmune thrombocytopenia (NAT). Of the 144 mothers who were Zwa-negative, 107 had Zwa antibodies--alone (94); with HLA antibodies (12); or with Bra antibodies (1). ⋯ Zwa-NAT was clinically the more severe (14% had intracranial haemorrhages) and responded well to either maternal platelet transfusions or intravenous IgG. In Bra-NAT intracranial haemorrhages were not observed and most children recovered without specific therapy.