Lancet
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Comparative Study
Cohort study on circumcision of newborn boys and subsequent risk of urinary-tract infection.
A decrease in risk of urinary-tract infection is one of the most commonly given reasons for circumcision of newborn boys. Previous studies have reported rates of UTI to be 10-20 times higher in uncircumcised than in circumcised boys. This population-based cohort study followed neonates in Ontario, Canada, prospectively to study the relation between circumcision and subsequent UTI risk. ⋯ Although our findings support the notion that circumcision may protect boys from UTI, the magnitude of this effect may be less than previously estimated.