Lancet
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Randomized Controlled Trial Comparative Study Clinical Trial
Transmyocardial laser revascularisation compared with continued medical therapy for treatment of refractory angina pectoris: a prospective randomised trial. ATLANTIC Investigators. Angina Treatments-Lasers and Normal Therapies in Comparison.
Transmyocardial revascularisation (TMR) is an operative treatment for refractory angina pectoris when bypass surgery or percutaneous transluminal angioplasty is not indicated. We did a prospective randomised trial to compare TMR with continued medication. ⋯ TMR lowered angina scores, increased exercise tolerance time, and improved patients' perceptions of quality of life. This operative treatment provided clinical benefits in patients with no other therapeutic options.
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Fomepizole is an effective alternative to ethanol in the treatment of ethylene glycol poisoning. In a series of 38 acute poisonings without renal failure, fomepizole obviated the need for haemodialysis.