Lancet
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Randomized Controlled Trial Multicenter Study
Parent-mediated communication-focused treatment in children with autism (PACT): a randomised controlled trial.
Results of small trials suggest that early interventions for social communication are effective for the treatment of autism in children. We therefore investigated the efficacy of such an intervention in a larger trial. ⋯ UK Medical Research Council, and UK Department for Children, Schools and Families.
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Comparative Study
Gene-environment interactions in 7610 women with breast cancer: prospective evidence from the Million Women Study.
Information is scarce about the combined effects on breast cancer incidence of low-penetrance genetic susceptibility polymorphisms and environmental factors (reproductive, behavioural, and anthropometric risk factors for breast cancer). To test for evidence of gene-environment interactions, we compared genotypic relative risks for breast cancer across the other risk factors in a large UK prospective study. ⋯ Cancer Research UK and the UK Medical Research Council.