Lancet
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Randomized Controlled Trial Multicenter Study
Effect of early neonatal vitamin A supplementation on mortality during infancy in Ghana (Neovita): a randomised, double-blind, placebo-controlled trial.
Results of randomised controlled trials of newborn (age 1-3 days) vitamin A supplementation have been inconclusive. The WHO is coordinating three large randomised trials in Ghana, India, and Tanzania (Neovita trials). We present the findings of the Neovita trial in Ghana. ⋯ Bill & Melinda Gates Foundation grant to the WHO.
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Randomized Controlled Trial Multicenter Study
Latanoprost for open-angle glaucoma (UKGTS): a randomised, multicentre, placebo-controlled trial.
Treatments for open-angle glaucoma aim to prevent vision loss through lowering of intraocular pressure, but to our knowledge no placebo-controlled trials have assessed visual function preservation, and the observation periods of previous (unmasked) trials have typically been at least 5 years. We assessed vision preservation in patients given latanoprost compared with those given placebo. ⋯ Pfizer, UK National Institute for Health Research Biomedical Research Centre.