Lancet
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Randomized Controlled Trial Multicenter Study
Eliglustat compared with imiglucerase in patients with Gaucher's disease type 1 stabilised on enzyme replacement therapy: a phase 3, randomised, open-label, non-inferiority trial.
The mainstay of treatment for Gaucher's disease type 1 is alternate-week infusion of enzyme replacement therapy (ERT). We investigated whether patients stable on such treatment would remain so after switching to oral eliglustat, a selective inhibitor of glucosylceramide synthase. ⋯ Genzyme, a Sanofi company.
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Biography Historical Article
Christina Roberto: taking a broad view on combating obesity.