Lancet
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Metastatic bone disease is a frequent complication of advanced non-small-cell lung cancer and causes skeletal-related events which result in a poor prognosis. A standard method to assess the therapeutic response of bone metastases does not currently exist. We used dynamic contrast-enhanced MRI to obtain quantitative measures to assess the suitability of this technique to gauge therapeutic response to vinorelbine-cisplatin plus rh-endostatinfor previously untreated non-small cell lung cancer with bone metastases. ⋯ National Natural Science Foundation of China [grant number 81201628].
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Severe middle cerebral artery infarction is defined as an acute infarction in the entire middle cerebral artery territory. Several case series have indicated that decompressive hemicraniectomy for severe middle cerebral artery infarction is lifesaving. However, data concerning the long-term functional outcome are insufficient. We did a systematic review and meta-analysis to assess the efficacy of decompressive hemicraniectomy for patients with severe middle cerebral artery infarction. ⋯ None.
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The health promotion model (HPM) is widely used in promoting lifestyle changes. Metabolic syndrome, the combination of multiple cardio-metabolic risk factors, has imposed heavy burden to the Chinese health-care system. Lifestyle intervention, especially exercise, is recommended as the primary intervention for management of metabolic syndrome. However, HPM has not been used in the population with metabolic syndrome. We assessed the effectiveness of a health promotion programme guided by HPM on self-efficacy and practice of exercise in Chinese people with metabolic syndrome. ⋯ None.
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More than 30 face transplantations have been done worldwide since 2005 but no documented long-term follow-up has been reported in the literature. We aimed to answer remaining question about the long-term risks and benefits of face transplant. ⋯ Protocole Hospitalier de Recherche Clinique (PHRC) National.
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Primary angle-closure glaucoma is a leading cause of irreversible blindness worldwide. In early-stage disease, intraocular pressure is raised without visual loss. Because the crystalline lens has a major mechanistic role, lens extraction might be a useful initial treatment. ⋯ Medical Research Council.