Lancet
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The measurement of quality-adjusted life-years (QALYs) forms a key component of cost-utility evaluation in cancer intervention; however, detailed data for utility weights by cancer type and health status are still scarce both in China and other regions. The aim of this study was to systematically evaluate utility scores in relation to the most common six cancers in China in 2012 (lung, breast, colorectal, oesophageal, liver, and stomach cancer). ⋯ The National Health and Family Plan Committee of China.
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Patient safety culture affects hospital safety and performance. The Hospital Survey on Patient Safety Culture (HSOPSC) is widely used to assess the safety culture in hospital and unit level. We aimed to assess strengths and weaknesses of surgical departments compared with others in county hospitals of China with HSOPSC. ⋯ Chinese National Health and Family Planning Commission (grant 20131577).
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The rising incidence and mortality of colorectal cancer (CRC) in China highlights the pressing need for population-based screening. Flexible sigmoidoscopy (FS) is becoming increasingly popular as a primary screening tool; and in many regions of China, colonoscopy capacity is limited. However, FS is preferred for patients with a low risk of advanced proximal neoplasia (APN; ie, higher numbers needed to screen [NNS], since the test predominantly examines the distal colon. Tailoring endoscopic screening based on the risk of APN is necessary, especially in resource-deprived regions. Since old age and female sex are two important CRC risk factors, we hypothesised that younger Chinese women aged 50-59 years had a significantly lower APN rate than did older Chinese men. ⋯ None.
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DNA methylation has been implicated in the pathology of obesity, but little is known about such epigenetic variants in Chinese people. We conducted an epigenome-wide analysis of methylation at CpG sites in relation to body mass index (BMI), waist circumference (WC) and waist-to-hip ratio (WHR) among Chinese adult populations. ⋯ This study was supported by the Specific Research Project of Health Public Service, Ministry of Health, China (201002007, 201502006) and Key Grant Project of Chinese Ministry of Education (310006).
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Shared decision-making is known to facilitate quality care, but little research has been done to explore this issue in mainland China. This study aimed to assess the preferred and perceived involvement in decision-making among patients considering cataract surgery, which is the most commonly performed procedure worldwide. ⋯ National Natural Science Foundation of China (81200685); National Natural Science Foundation of China (81100686); Science and Technology Program of Guangzhou, China (15570001); and Fundamental Research Funds of the State Key Laboratory of Ophthalmology.