Lancet
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Randomized Controlled Trial Pragmatic Clinical Trial
Impregnated central venous catheters for prevention of bloodstream infection in children (the CATCH trial): a randomised controlled trial.
Impregnated central venous catheters are recommended for adults to reduce bloodstream infections but not for children because there is not enough evidence to prove they are effective. We aimed to assess the effectiveness of any type of impregnation (antibiotic or heparin) compared with standard central venous catheters to prevent bloodstream infections in children needing intensive care. ⋯ National Institute for Health Research, UK.
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Randomized Controlled Trial
Effect of Plasmodium inactivation in whole blood on the incidence of blood transfusion-transmitted malaria in endemic regions: the African Investigation of the Mirasol System (AIMS) randomised controlled trial.
Transfusion-transmitted malaria is a frequent but neglected adverse event in Ghana. We did a randomised controlled clinical trial to assess the efficacy and safety of a whole blood pathogen reduction technology at preventing transfusion transmission of Plasmodium spp parasites. ⋯ Terumo BCT Inc.