Lancet
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Randomized Controlled Trial Multicenter Study Comparative Study
Pembrolizumab versus paclitaxel for previously treated, advanced gastric or gastro-oesophageal junction cancer (KEYNOTE-061): a randomised, open-label, controlled, phase 3 trial.
Patients with advanced gastric or gastro-oesophageal junction cancer that progresses on chemotherapy have poor outcomes. We compared pembrolizumab with paclitaxel in patients with advanced gastric or gastro-oesophageal junction cancer that progressed on first-line chemotherapy with a platinum and fluoropyrimidine. ⋯ Merck Sharp & Dohme, a subsidiary of Merck & Co.
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Observational Study
Causes and incidence of community-acquired serious infections among young children in south Asia (ANISA): an observational cohort study.
More than 500 000 neonatal deaths per year result from possible serious bacterial infections (pSBIs), but the causes are largely unknown. We investigated the incidence of community-acquired infections caused by specific organisms among neonates in south Asia. ⋯ Bill & Melinda Gates Foundation.