Lancet
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Road safety interventions addressing speed would save about 350,000 lives globally each year.
pearl -
Randomized Controlled Trial Multicenter Study
Intravenous tenecteplase compared with alteplase for acute ischaemic stroke in Canada (AcT): a pragmatic, multicentre, open-label, registry-linked, randomised, controlled, non-inferiority trial.
Intravenous thrombolysis with alteplase bolus followed by infusion is a global standard of care for patients with acute ischaemic stroke. We aimed to determine whether tenecteplase given as a single bolus might increase reperfusion compared with this standard of care. ⋯ Canadian Institutes of Health Research, Alberta Strategy for Patient Oriented Research Support Unit.