Lancet
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Randomized Controlled Trial Clinical Trial
Electrical spinal-cord stimulation for painful diabetic peripheral neuropathy.
Conventional treatment for painful peripheral diabetic neuropathy is largely symptomatic and often ineffective, with unacceptable side-effects. We tested electrical spinal-cord stimulation for the management of chronic neuropathic pain. ⋯ Electrical spinal-cord stimulation offers a new and effective way of relieving chronic diabetic neuropathic pain and improves exercise tolerance. The technique should be considered in patients with neuropathic pain who do not respond to conventional treatment.
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Randomized Controlled Trial Comparative Study Clinical Trial
Effect of hydroxyethylstarch in brain-dead kidney donors on renal function in kidney-transplant recipients.
Hydroxyethylstarch used as a plasma-volume expander in brain-dead kidney donors has been suggested to induce osmotic-nephrosis-like lesions. We have studied its effect on kidney-transplant function. ⋯ These data suggest that hydroxyethylstarch used as a plasma-volume expander in brain-dead donors impairs immediate renal function in kidney-transplant recipients.