Lancet
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Comparative Study
Exposure to power-frequency magnetic fields and the risk of childhood cancer. UK Childhood Cancer Study Investigators.
Previous studies have suggested an association between exposure to power-frequency electromagnetic fields (EMF) and the development of childhood malignant disease, especially leukaemia and tumours of the central nervous system. We investigated the relation between all childhood cancer and exposure to power-frequency magnetic fields. ⋯ This study provides no evidence that exposure to magnetic fields associated with the electricity supply in the UK increases risks for childhood leukaemia, cancers of the central nervous system, or any other childhood cancer.
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Randomized Controlled Trial Comparative Study Clinical Trial
Supine body position as a risk factor for nosocomial pneumonia in mechanically ventilated patients: a randomised trial.
Risk factors for nosocomial pneumonia, such as gastro-oesophageal reflux and subsequent aspiration, can be reduced by semirecumbent body position in intensive-care patients. The objective of this study was to assess whether the incidence of nosocomial pneumonia can also be reduced by this measure. ⋯ The semirecumbent body position reduces frequency and risk of nosocomial pneumonia, especially in patients who receive enteral nutrition. The risk of nosocomial pneumonia is increased by long-duration mechanical ventilation and decreased consciousness.
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Randomized Controlled Trial Clinical Trial
Cardiac arrhythmias in children during outpatient general anaesthesia for dentistry: a prospective randomised trial.
Deaths in children associated with outpatient general dental anaesthesia may be attributable to sudden cardiovascular collapse precipitated by ventricular arrhythmias. A causal link between halothane anaesthesia, ventricular arrhythmias, and deaths has been suggested. We did a prospective, randomised trial to investigate the frequency and character of arrhythmias during anaesthesia with halothane and the alternative anaesthetic agent, sevoflurane. ⋯ There was a strong association between halothane and ventricular arrhythmias, especially ventricular tachycardia. The use of sevoflurane in preference to halothane could contribute to a decline in morbidity and mortality associated with dental anaesthesia.