Medicine
-
Observational Study
Development and validation of the hypertensive intracerebral hemorrhage prognosis models.
To develop and validate the prognosis model of hypertensive intracerebral hemorrhage based on admission characteristics, which would be applied to predict the 3-month outcome. For developing the prognosis models, we studied data from 325 patients with retrospectively consecutive hypertensive intracerebral hemorrhage admitted between 2012 and 2016. The predictive value of admission characteristics was tested in logistic regression models, presenting 3-month outcome as the primary outcome. ⋯ The receiver operating characteristic curve was used to analyze the discriminant ability of model A, model A + B, and model A + B + C. Specifically, the area under the receiver operating characteristic curve increased from 0.816 (model A; 95% CI, 0.760-0.872) to 0.913 (model A + B + C; 95% CI, 0.881-0.946), and the models were not overoptimistic and were applicably confirmed by internal and external validations respectively. This prognosis model could be used to predict the prognosis of patients with hypertensive intracerebral hemorrhage early, simply and accurately, contributing to the clinical treatment eventually.
-
Case Reports
Colon cancer and IgG4-related disease with orbital inflammation and bilateral optic perineuritis: A case report.
Immunoglobulin G4-related disease (IgG4-RD) is an inflammatory condition of unknown cause. Cancer might be related to the development of certain IgG4-RD but to date, little literature documents it. ⋯ This case raises the possibility of IgG4-RD being a paraneoplastic syndrome in some patients. Cancer screening should probably be performed in some elderly patients diagnosed with IgG4-RD.
-
The purpose of the present study was to determine whether Internet overuse was associated with empathic ability in college students. A total 261 participants (145 males and 116 females; mean age of 21.93 years) completed Empathy Quotient (EQ), Young's Internet Addiction Test (IAT), and questionnaires about demographic data and internet using patterns. Of these 261 subjects, 85 (32.5%) were categorized as over-users. ⋯ EQ score was found to have positive correlation with time spent in Internet use and the number of close friends. Results of the present study suggest that conventional Internet use is positively associated with empathic ability in interpersonal relationships. Therefore, such positive association between Internet use and empathic ability should be considered when evaluating possible problematic internet use.
-
In psychiatric disorders, interindividual differences in cytochrome P450 (CYP)2D6 (CYP2D6) enzymatic activity could be responsible of adverse drug reactions (ADRs) and therapeutic failures (TFs) for CYP2D6-metabolized drugs, contributing to the periodical hospital readmissions of the revolving door (RD) condition. ⋯ Our findings may suggest that CYP2D6 clinically relevant genotypes may be involved in the unwanted outcomes observed in RD patients with BD.
-
Syncope is a complicated clinical condition involving various diseases. Syncope due to myxoma-like right atrial thrombus is rarely seen in patient without structural heart disease. ⋯ This patient had a past medical history of right femoral neck fracture, which might be responsible for the formation of the myxoma-like right atrial thrombus. We should always consider echocardiography examination in syncope patient at risk of thrombus formation.