Medicine
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High rates of co-existing irritable bowel syndrome (IBS) and headache have been reported in western countries. We investigated that comorbidity in individuals in Japan, along with anxiety and depression in subjects with and without IBS symptoms and/or headache. This cross-sectional study was performed from April 2012 to January 2013 at the Matsue Seikyo General Hospital Health Check Center. ⋯ Unlike anxiety, the percentage of subjects with depression was not significantly different among the IBS/non-headache, non-IBS/headache, and IBS/headache groups. Subjects with IBS symptoms had a higher rate of co-existing headache as compared to those without IBS. Furthermore, those with comorbid IBS symptoms and headache had a greater association with anxiety than with depression, as compared to those with only IBS or headache.
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Cardiovascular disease is the main cause of death in patients with chronic kidney disease (CKD). Studies have found that hypothyroidism can significantly increase cardiovascular risk. Meanwhile, hypothyroidism is a common complication of CKD, but the correlation between hypothyroidism and cardiovascular risk in CKD patients has not been verified and paid enough attention. We therefore plan to conduct a systematic review and meta-analysis to explore whether hypothyroidism was independently predictive for the cardiovascular risk in patients with CKD. ⋯ INPLASY2020100022.
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Gastroparesis affects the quality of life of many patients, but there is no effective treatment. Now, complementary and alternative medicine originated from China is gradually accepted by the world because of its unique treatment principles and relatively safe treatment methods. However, at present, there is still a lack of more definitive clinical application evidence for the treatment of gastroparesis with complementary and alternative medicine to confirm the safety and efficacy of complementary and alternative medicine in the treatment of gastroparesis caused by various causes. More comprehensive and stronger evidence-based medicine evidence is needed. ⋯ The research has been registered and approved on the INPLASY.COM website. The registration number is INPLASY2020100033.
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Although social anxiety as a ubiquitous emotion impacting people's social behaviors has aroused much researchers' interest in exploring its cognitive behavioral model, no previous study has focused on soldiers with different social anxiety within the context of the specific military environment. To explore the associations between social anxiety and interpersonal information processing concerted on interpretation and judgment, the study may provide an intervention point for soldiers to ameliorate social anxiety and accommodate to the military-life environment. A self-reported questionnaire and 2 behavioral tasks were conducted in the cross-section study to explore the associations. ⋯ Soldiers' social anxiety has an influence on processing military-life interpersonal information, and it plays a certain intermediary role in the associations between low abidance and negative interpretation bias. The stronger negative interpretation bias than positive bias of soldiers, the higher social anxiety they could show with the less possibility to abide, which might result in behaviors against the military collective requirements. Social anxiety has the primary effect on the abidance of soldiers; hence, in the future, the interpretation bias modification could be a plausible cognitive-behavior therapy to help soldiers ameliorate social anxiety, thus contributing to enhancing their sense of belonging to the troops and accommodation to military life.
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Lipid abnormalities are an important cause of premature atherosclerosis in patients with systemic lupus erythematosus (SLE). This longitudinal study investigates the changes in lipid profile and arterial stiffness with SLE disease activity index (SLEDAI) reduction. Fifty one female SLE patients with baseline SLEDAI ≥ 6 and SLEDAI reduction >3 at 1-year follow-up were included. ⋯ Significant correlations were found between the reductions in ESR and TG, and SLEDAI and mean baPWV, with adjustment to age, disease duration, blood pressure, and medications (prednisone, immunosuppressants and ARB/ACEI). SLE patients experiencing SLEDAI reductions showed improvements in arterial stiffness. This finding may provide insight into the beneficial effects of reducing SLEDAI on atherosclerosis risk in SLE.