Medicine
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Microdeletion syndromes occur from deletion of 5Mb of a chromosome in approximately 5% of patients with unexplained intellectual disability. Interstitial microdeletions at bands 1p33 and 1p32.2 of the short arm of chromosome 1 are rare and have not been previously reported in relation to disease. ⋯ The spectrum of phenotypes this case presented with are likely to be caused by 1p33p32.2 deletion which could represent a new microdeletion syndrome.
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The prevalence of diabetes mellitus and impaired fasting glucose is rapidly increasing in the recent years. Hyperglycemia associated atherosclerosis and other complications are posing a serious threat to human health. The present study aimed to analyze the blood glucose distribution characteristics within a large size of health examination population of Sichuan province, China. ⋯ The percentage of cases with high glucose levels was significantly higher in males than that in females since 2009 to 2017. Moreover, the blood glucose levels and the percentage of high glucose levels in aged population were significantly higher than those in younger population every year. The health examination population showed increased percentage of blood glucose levels, and so regular physical examination and glucose control are highly important in aged population.
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Randomized Controlled Trial
The efficacy and safety of Clostridium butyricum and Bacillus coagulans in Helicobacter pylori eradication treatment: An open-label, single-arm pilot study.
Helicobacter pylori (H pylori) infection plays a critical role in gastritis-associated diseases, gastroduodenal ulcers, and even gastric cancer. Studies have shown that probiotics may exhibit antagonistic activity against H pylori. ⋯ C butyricum and B coagulans may effectively inhibit H pylori to some extent, with rare adverse events, and thus may reduce the burden of antibiotic resistance.
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The purpose of this study is to evaluate the efficacy and safety of complementary and alternative medicine in the treatment of autism spectrum disorder. ⋯ OSF Registries, DOI: 10.17605/OSF.IO/ HA97R (https://osf.io/ha97r).
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Bacterial infection has been identified as one of the most significant complications of liver transplantation (LT). Multidrug-resistant (MDR) gram-negative bacteria (GNB) infection remains problematic issue following LT in the adults. However, data in children are scarce. ⋯ This study has highlighted the high prevalence rate of MDR-GNB infection after pediatric LT. Therefore, caution on the emergence of MDR-GNB infection should be paid in at-risk children. Moreover, knowledge regarding the prevalence of MDR-GNB infection and resistant patterns is essential for guideline development to prevent and minimize the risk of MDR-GNB infection in this group of patients.