Medicine
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This study aimed to evaluate the diagnostic value of automated breast volume scanner (ABVS) combined with virtual touch tissue quantification (VTQ) in the differential diagnosis of breast lesions. In this retrospective study, 183 patients (mean age, 49.8 ± 8.2 years) with 218 breast lesions underwent ABVS, VTQ, and mammography (MG). All lesions were confirmed by postoperative histopathology. ⋯ The AUC of ABVS-VTQ was higher than that of the other examinations alone. The detection rate of ABVS (100%, 218/218) was higher than that of MG (78.89%, 172/218), and the difference was statistically significant (χ2 = 51.426, P < .001). The combined application of ABVS and VTQ can improve the accuracy and specificity of the diagnosis and is a promising ultrasound method for the differential diagnosis of breast lesions.
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We aimed to assess the respiratory virus characteristics and forecasts among young children with acute respiratory tract infection (ARTI) in west China. This retrospective study investigated the epidemic characteristics of respiratory viruses among 11,813 paediatric ARTI patient samples (mean age, 2.25 years) between March 2018 and March 2020. The ratio of boys to girls was 1.36. ⋯ During the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic, isolation measures led to a decline in the number of ARTI cases. This study provides surveillance data of the respiratory viruses in west China. It could guide medical staff in implementing necessary prevention and management strategies before future viral outbreaks.
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Gliomas have the highest incidence among primary brain tumors, and the extracellular matrix (ECM) plays a vital role in tumor progression. We constructed a risk signature using ECM-related genes to predict the prognosis of patients with gliomas.mRNA and clinical data from glioma patients were downloaded from The Cancer Genome Atlas (TCGA), Genotype-Tissue Expression (GTEx) and Chinese Glioma Genome Atlas (CGGA) databases. Differentially expressed ECM-related genes were screened, and a risk signature was built using least absolute shrinkage and selection operator (LASSO) Cox regression. ⋯ This risk signature could be an effective tool for predicting glioma prognosis. This study did not require ethical approval. We will disseminate our findings by publishing results in a peer-reviewed journal.
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Case Reports
Acute fatty liver of pregnancy causes severe acute pancreatitis and stillborn fetus: A case report.
Acutefatty liver of pregnancy (AFLP) is a potentially fatal obstetric emergency characterized by acute hepatic failure secondary to fatty infiltration. The resultant effects include coagulopathy, electrolyte abnormalities, and multisystem organ dysfunction. Pancreatitis typically develops after the onset of renal and hepatic dysfunction. Pancreatitis has been suggested as a poor prognostic indicator because it is associated with more adverse outcomes. ⋯ Once AFLP is highly suspected or confirmed, the pregnancy should be terminated in time and active symptomatic management should be given.
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Post-viral olfactory dysfunction (PVOD) have been reported in infections caused by several respiratory viruses, especially in COVID-19 which influence severely the quality of life of affected subjects. Few study has been published on the treatment of PVOD. Traditional Chinese medicine (TCM) is an effective method for PVOD which effects and safety have been confirmed. Therefore, this study is aim to evaluate the effects of TCM on PVOD. ⋯ CRD42021238977.