Medicine
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The COVID-19 epidemic has placed a lot of mental burdens on school students, causing anxiety. Clinically, it has been found that the Yuji point (LU10) can relieve anxiety by regulating Qi. ⋯ Acupuncture at LU10s can regulate anxiety by upregulating or downregulating the relevant brain regions and networks. LU10s can be used to treat not only lung disorders but also related mental disorders.
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The correlation among circular RNAs (circRNAs), microRNAs, and messenger RNAs have gained increasing attention in recent years. However, the mechanism of such discoveries in colorectal cancer (CRC) is not yet elucidated. The present study aimed to clarify whether the novel circRNAs regulate the prognosis-related genes through the competing endogenous RNAs (ceRNA). ⋯ Immunohistochemical staining further validated that SCRIN1 was significantly higher in cancer than in adjacent normal tissues. Our study identified and primarily validated the hsa_circ_0046430/miR-6785-5p/SRCIN1 regulatory axis impacted on CRC prognosis, suggesting novel biomarkers and therapeutic targets for CRC patients. Further in-depth studies are essential to confirm the underlying ceRNA mechanism.
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Frailty can change the prognosis and treatment approach of chronic diseases. We, therefore, conducted this study to explore the relationship between frailty syndrome and blood pressure variability in the elderly. The clinical data of 150 elderly patients with debilitating syndrome admitted to the neurology department of our hospital from May 2021 to May 2022 were selected, and they were grouped according to Fried debilitation scale and divided into 50 cases each in the debilitation group, pre-debilitation group, and no-debilitation group. ⋯ Age, type of medication taken, co-morbidities, serum ALB, and HDL are influencing factors of debilitating syndrome. Serum ALB and HDL are protective factors against debilitating syndrome in the elderly. Age is an independent risk factor of debilitation in the elderly and increased fluctuation of blood pressure in the elderly can increase their risk of developing debilitating syndrome.
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The h-index is increasingly being used as a measure of individual research achievement (IRA). More than 4876 citing articles have been published and indexed in Web of Science. The articles citing the h-index that have made the greatest contribution to scientific academics are still unknown. It is also unclear which subject categories (SCs) can be classified based on their keywords. ⋯ A total of 7 visualizations were used to display the results in this study. Chord diagrams are suggested as a tool for future bibliographical studies to classify SCs Future bibliometrics with chord diagrams should not be limited to the topic of h-index-citing articles, as we did in this study.
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Patients with heart disease often feel helpless and anxious because of illnesses in their vital organs. Unfamiliar environment of the intensive care unit is another factor that increases patient anxiety. This study developed audiovisual media-based information on nursing after open-heart surgery and evaluated its effect on patients' post-surgery, with the aim of reducing patients' environmental stress, anxiety, and uncertainty. ⋯ There was a significant difference in anxiety between the mean pretest-posttest scores, with 0.39 ± 0.35 points in the experimental group, and -0.05 ± 0.58 points in the control group (t = 5.165, P < .001). On the other hand, there was a significant difference in uncertainty between the mean pretest-posttest scores, with 0.39 ± 0.4 points in the experimental group, and 0.24 ± 0.48 points in the control group (t = 4.541, P < .001). This finding indicates that providing audiovisual information regarding nursing before open-heart surgery is effective in reducing environmental stress, anxiety, and uncertainty in patients.