Medicine
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Adenoid cystic carcinoma (ACC) of orbit is a very rare epithelial tumor, often originating from the lacrimal glands. At the same time, treatment options are currently limited, such as radiation, chemotherapy. We report a case of a patient treated with antirotinib combined with radiotherapy. ⋯ Based on this, we hypothesized that radiation therapy in combination with anlotinib is effective for ACC or ACC metastases.
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Bladder diverticula (BD) can be classified into congenital and acquired forms, with the latter accounting for approximately 90% of all cases, primarily among male patients. Although BD-associated anatomical bladder outlet obstruction (BOO) is uncommon, existing literature suggests that congenital BD are more frequently observed in male children and rarely in female children. While around 70% of acquired BD are linked to BOO secondary to benign prostatic hyperplasia in male patients, clinical reports of female BD are less common. Furthermore, cases of female BD located posterior to the urethra, which lead to voiding difficulties, are exceedingly rare. ⋯ Female bladder outlet obstruction resulting from posterior urethral BD can be challenging to visualize during transurethral cystoscopy, especially with limited angulation, and may even be overlooked. Furthermore, conventional transvaginal diverticulectomy is often difficult to perform effectively. Therefore, laparoscopic bladder diverticulectomy, partial urethral croppingplasty, and cystoplasty are considered appropriate treatment options for such cases.
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With a high failure rate and multiple postoperative complications, the resection for tumors in the elbow and reconstruction present a formidable challenge to orthopedic surgeons. The maturation of 3-dimension (3D) printing technology has facilitated the preoperative design, intraoperative navigation, and reconstruction of bone defects in patients with complex malignant tumors of the elbow joint. In order to improve prognosis, we explored a method of tumor resection and elbow reconstruction aided by 3D printing technology in this research. ⋯ For patients with complex tumors in the elbow joint, 3D printing technology may assist in the precise excision of the tumor and provide an individualized elbow joint prosthesis that is more precise and effective than traditional surgery. It can accomplish a satisfactory treatment effect for patients when combined with early postoperative scientific rehabilitation training, so it is a method worth promoting.
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To identify the care needs of primary caregivers of colorectal cancer (CRC) patients and specify the characteristics of high-needs caregivers. A cross-sectional survey was conducted on the primary caregivers of CRC patients using the Comprehensive Needs Assessment Tool in Cancer Caregivers. The care needs and the characteristics of caregivers with high needs were identified using the Chi-square test and Logistic regression. ⋯ The characteristics of caregivers with high information needs included living in the city, on-the-job, a family per capita monthly income of <4000 yuan, and the CRC patients they took care of paid medical expenses through self-pay/public expense/rural insurance. In clinical settings, the information needs of primary caregivers of CRC patients should be given due attention. Particular attention should be paid to the primary caregivers of CRC patients who live in cities, are on-the-job, have a per capita monthly income of <4000 yuan, and pay medical expenses through self-pay/public/rural insurance.
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To evaluate the impact of a reduced iodine load using deep learning reconstruction (DLR) on the hepatic parenchyma compared to conventional iterative reconstruction (hybrid IR) and its consequence on the radiation dose and image quality. This retrospective monocentric intraindividual comparison study included 66 patients explored at the portal phase using different multidetector computed tomography parameters: Group A, hybrid IR algorithm (hybrid IR) and a nonionic low-osmolality contrast agent (350 mgI/mL); Group B, DLR algorithm (DLR) and a nonionic iso-osmolality contrast agent (270 mgI/mL). We recorded the attenuation of the liver parenchyma, image quality, and radiation dose parameters. ⋯ However, for both the contrast-to-noise ratio (CNR) and CNR liver/PV no statistical difference was found, even if the CNR liver/PV ratio was slightly higher for group A. The mean dose-length product and computed tomography dose index volume values were significantly lower with DLR, corresponding to a radiation dose reduction of 36% for the DLR. Using a DLR algorithm for abdominal multidetector computed tomography with a low iodine load can provide sufficient enhancement of the liver parenchyma up to 100 HU in addition to the advantages of a higher image quality, a better signal-to-noise ratio and a lower radiation dose.