Medicine
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Randomized Controlled Trial
Traditional Chinese herbal compound as complementary treatment for nonspecific low back pain: A randomized controlled trial.
This prospective randomized controlled trial was designed to evaluate the clinical efficacy and safety of Bu Shen Tong Luo herbal compound as a complementary treatment for nonspecific low back pain (NSLBP). ⋯ Both BSTL herbal compound and celecoxib are effective and safe in the clinical treatment of NSLBP, and BSTL herbal compound had unique advantages in the treatment of HSBZ syndrome type of NSLBP especially in waist function improvement.
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Randomized Controlled Trial
Effect of Baduanjin exercise on acute myocardial infarction in patients with anxiety and depression after percutaneous coronary intervention: A randomized controlled trial.
Acute myocardial infarction (AMI) is the most severe type of coronary heart disease and patients often require percutaneous coronary intervention (PCI). However, anxiety and depression are common complications of PCI. ⋯ Baduanjin exercise for 8 weeks improved the cardiac function and mental state of patients with anxiety and depression after PCI for AMI. Through this study, we aim to provide reliable evidence in support of the beneficial effects of Baduanjin exercise on cardiac function and anxiety-depression, contributing to evidence-based medicine.
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Randomized Controlled Trial
Clinical study of different frequency transcranial magnetic stimulation combined with paroxetine in the treatment of poststroke depression with insomnia.
Study the treatment of poststroke depression and insomnia using varied repetitive transcranial magnetic stimulation (rTMS) frequencies alongside paroxetine. Aim to enhance rTMS effectiveness for depression, insomnia, neurological impairment, and daily living skills. ⋯ Low-frequency rTMS combined with medication has a better therapeutic effect on the insomnia symptoms of PSD, while high-frequency rTMS combined with medication has a more pronounced therapeutic effect on the depressive symptoms of PSD. Both high-frequency and low-frequency rTMS have an improving effect on neurofunctional deficits and activities of daily living.
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Randomized Controlled Trial
Application of extracorporeal shockwave to regulate subchondral bone homeostasis through tumor necrosis factor-α/hypoxia-inducible factor-1α/vascular endothelial growth factor signaling pathway in treatment of talus bone marrow edema.
To investigate the effect of extracorporeal shock wave on the treatment of talus bone marrow edema by regulating subchondral bone homeostasis through tumor necrosis factor-α (TNF-α)/hypoxia-inducible factor-1α (HIF-1α)/vascular endothelial growth factor (VEGF) signaling pathway. A total of 81 patients with talus bone marrow edema admitted to our hospital from May 2019 to May 2021 were studied and divided into control group (n = 40) and extracorporeal shock group (n = 41) according to random number table method. The control group was given conventional treatment, and the extracorporeal shock group was combined with extracorporeal shock wave therapy on the basis of the control group. ⋯ After 5 months of treatment, the expressions of TNF-α and HIF-1α were decreased in both groups, and the extracorporeal shock group was lower than the control group, VEGF was increased, and the extracorporeal shock group was higher than the control group (P < .05), and the western blot expression levels of TNF-α, HIF-1α and VEGF in the extracorporeal shock group were higher than the control group (P < .05). The dorsiflexion motion and plantar flexion motion of both groups were increased, and the extracorporeal shock group was higher than the control group (P < .05). Extracorporeal shock wave therapy can regulate subchondral bone homeostasis through TNF-α/HIF-1α/VEGF signaling pathway to treat talus bone marrow edema, reduce the pain degree of talus bone marrow edema, and improve ankle joint function.
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Comparative Study Observational Study
Comparison of two formulas for calculating intraocular lens in patients with angle-closure glaucoma.
This study compares the accuracy of SRK/T and Barrett Universal II intraocular lens (IOL) measurement formulas for cataract phacoemulsification combined with intraocular lens implantation in angle-closure glaucoma (ACG) patients. Prospective serial case studies were conducted. A total of 146 patients (146 eyes) with ACG complicated with cataract who underwent cataract surgery with atrial angle closure ≤180° were observed. ⋯ Axis length was negatively correlated with SRK/T formula and Barrett Universal II formula absolute refractive error value (ME) (group A: r = -0.740, P < .001; group B: r = -0.532, P < .001), there was A significant negative correlation between absolute refractive error value and anterior chamber depth in both groups (group A: r = -0.382, P = .001; group B: r = -0.358, P = .002). The cataract phacoemulsification combined with intraocular lens implantation is safe and effective for ACG patients with cataract. For such patients, the Barrett Universal II intraocular lens measurement formula may be more accurate after surgery.