JAMA : the journal of the American Medical Association
-
Preclinical and epidemiological studies indicate a potential chemopreventive role of statins in epithelial ovarian cancer risk. ⋯ Genetically proxied inhibition of HMG-CoA reductase was significantly associated with lower odds of epithelial ovarian cancer. However, these findings do not indicate risk reduction from medications that inhibit HMG-CoA reductase; further research is needed to understand whether there is a similar association with such medications.