JAMA : the journal of the American Medical Association
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Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality in the US. ⋯ The findings of this targeted evidence update are generally consistent with the findings of the previous systematic review supporting the 2016 USPSTF recommendation. Evidence of pharmacologic treatment was still largely limited to persons with moderate airflow obstruction, and there was no consistent benefit observed for a range of nonpharmacologic interventions in mild to moderate COPD or in minimally symptomatic persons with COPD.