Journal of the American Veterinary Medical Association
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J. Am. Vet. Med. Assoc. · May 1983
Minimal alveolar concentrations for halothane, enflurane, and isoflurane in the cat.
The minimal alveolar concentrations for halothane, enflurane, and isoflurane in the domestic cat were found to be 1.19 +/- 0.05 (SEM)%, 2.37 +/- 0.06%, and 1.61 +/- 0.04%, respectively. During the potency studies, it was observed that enflurane and isoflurane resulted in shorter wake-up times, compared with halothane. However, enflurane and isoflurane produced electroencephalographic (EEG) and clinical signs of CNS irritability (EEG spiking, myoclonus) in normocapnic or mildly hypocapnic cats. In addition, enflurane and isoflurane caused greater airway irritability (coughing, salivation) than did halothane.
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J. Am. Vet. Med. Assoc. · Aug 1982
Acid-base and electrolyte disturbances in dogs with gastric dilatation-volvulus.
Blood samples from 57 dogs with gastric dilatation-volvulus were analyzed for acid-base, blood gas (P02, Pco2), and electrolyte abnormalities. Although a variety of pH, blood gas, and electrolyte disturbances were recorded, metabolic acidosis and hypokalemia were common findings. ⋯ Attempts to correlate the severity of pH, blood gas, and electrolyte derangements with duration of disease, heart rate, respiratory rate, or a mathematical index based on the sum of these variables were unsuccessful. It was concluded that acid-base and fluid therapy for dogs with gastric dilatation-volvulus should be based on accurate determinations of blood pH and serum bicarbonate and electrolyte concentrations.