Journal of neurosurgery
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The authors sought to evaluate local tumor control, complications, and progression-free survival in patients harboring low-grade gliomas who were treated with Leksell gamma knife surgery (GKS). ⋯ Relatively high local tumor control with minimal complications was achieved.
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Journal of neurosurgery · Jan 2005
Gamma knife surgery for trigeminal neuralgia: improved initial response with two isocenters and increasing dose.
The authors sought to evaluate the initial response of trigeminal neuralgia (TN) to gamma knife surgery (GKS) based on the number of shots delivered and radiation dose. ⋯ Gamma knife surgery is an effective therapy for TN. Initial response rates appear to correlate with the number of shots and dose.
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Journal of neurosurgery · Jan 2005
Treatment of essential trigeminal neuralgia with gamma knife surgery.
The authors present the long-term follow-up results (minimum 5 years) of patients with essential trigeminal neuralgia (TN) who were treated with gamma knife surgery (GKS). ⋯ The initial success rate of pain relief was high and comparable to that reported in other studies. A higher than usual incidence of sensory impairment after GKS could be the long duration of follow-up study and due to the detailed neurological examination.
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Journal of neurosurgery · Jan 2005
Gamma knife thalamotomy for movement disorders: evaluation of the thalamic lesion and clinical results.
The authors studied the effects of gamma knife thalamotomy (GKT) on Parkinson disease-related tremor and essential tremor before and after reloading of radioactive cobalt. ⋯ The shorter delay in clinical improvement and smaller lesion size may be related to an increased radiation dose.
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Journal of neurosurgery · Jan 2005
Computational model for the estimation of the extracranial doses received during Leksell gamma knife model C treatment.
Extracranial doses received by patients undergoing Leksell gamma knife surgery (GKS) can be of clinical concern. Therefore, the ability to preestimate peripheral doses received outside the treatment field during the GKS would be beneficial and could be used for the optimization of treatment planning by providing a reference for practitioners to calculate the extracranial dose burden to the body before the start of treatment. ⋯ The peripheral dose depended on the collimator size with a logarithmic dependence on collimator size and a linear dependence on the number of shots. This model can be used for the estimation of peripheral doses with a total error less than 20%. This information can help clinicians with treatment planning optimization, especially in patients with long survival expectancy.