Journal of neurosurgery
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Journal of neurosurgery · Jan 2005
Evaluation of a new concept for the management of skull base chordomas and chondrosarcomas.
Chordomas and chondrosarcomas of the skull base are rare locally invasive tumors associated with high recurrence rates. The aim of this study was to evaluate the concept of microsurgical tumor volume reduction followed by early gamma knife surgery (GKS). ⋯ Results of this treatment strategy are encouraging but the efficacy of this multimodal treatment combining surgery and early GKS requires a longer follow up.
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Journal of neurosurgery · Jan 2005
Postoperative cerebral hyperperfusion associated with impaired cognitive function in patients undergoing carotid endarterectomy.
Cognitive impairment occurs in 20 to 30% of patients following carotid endarterectomy (CEA). The purpose of the present study was to determine whether postoperative cerebral hyperperfusion is associated with impairment of cognitive function in patients undergoing that procedure. ⋯ Postoperative cerebral hyperperfusion is associated with impairment of cognitive function in patients undergoing CEA. Furthermore, the development of hyperperfusion syndrome is associated with the persistence of postoperative cognitive impairment.
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Journal of neurosurgery · Jan 2005
Long-term results of Leksell gamma knife surgery for trigeminal schwannomas.
The authors evaluated the long-term efficacy of gamma knife surgery (GKS) in patients with trigeminal schwannomas. ⋯ Radiosurgery proved to be an effective treatment for small- and medium-sized trigeminal schwannomas. Some larger tumors are also suitable for radiosurgery if there is no significant brainstem compression.
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Journal of neurosurgery · Jan 2005
A simple method for predicting imaging-based complications following gamma knife surgery for cerebral arteriovenous malformations.
The authors studied the relationship between dose planning parameters and complications in the treatment of cerebral arteriovenous malformations (AVMs). ⋯ The integral dose could be used as a guideline for the prescription dose. Arguments are made for maximizing the prescription dose for the long-term safety of the patient.
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Journal of neurosurgery · Jan 2005
Prolonged survival in a subgroup of patients with brain metastases treated by gamma knife surgery.
The authors analyzed the factors involved in determining prolonged survival (> or = 24 months) in patients with brain metastases treated by gamma knife surgery (GKS). ⋯ Aggressive local therapy with GKS, repeated GKS, and GKS plus surgery can achieve increased survival in a subgroup of patients with stable primary disease, no third-organ involvement, and long primary-brain secondary intervals.