Journal of neurosurgery
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Journal of neurosurgery · Feb 2016
Time-delayed contrast-enhanced MRI improves detection of brain metastases and apparent treatment volumes.
Contrast-enhanced MRI is the preeminent diagnostic test for brain metastasis (BM). Detection of BMs for stereotactic radiosurgery (SRS) planning may improve with a time delay following administration of a high-relaxivity agent for 1.5-T and 3-T imaging systems. Metastasis detection with time-delayed MRI was evaluated in this study. ⋯ In patients who are being prepared for SRS of BMs, delayed MRI after contrast injection revealed more targets that needed treatment. In addition, apparent treatment volumes increased with a time delay. To avoid missing tumors that could be treated at the time of planned SRS and resultant "treatment failures," the authors recommend that postcontrast MR images be acquired between 10 and 15 minutes after injection in patients undergoing SRS for treatment of BMs.
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Journal of neurosurgery · Feb 2016
Editorial CommentEditorial: Randomized clinical trials and neurosurgery.