European urology
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Multicenter Study
The burden of urinary incontinence and urinary bother among elderly prostate cancer survivors.
Data describing urinary health in elderly, community-dwelling prostate cancer (PCa) survivors are limited. ⋯ Compared with their peers without PCa, elderly PCa survivors had a two-fold to five-fold greater prevalence of urinary incontinence, which rose with increasing survivorship duration. Observation, surgery, and ADT were each associated with increased urinary bother. These data suggest a substantially greater burden of urinary health problems among elderly PCa survivors than previously recognized.
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Randomized Controlled Trial Multicenter Study
Screening for prostate cancer: results of the Rotterdam section of the European randomized study of screening for prostate cancer.
Evidence from randomized trials on the effects of screening for prostate cancer (PCa) on disease-specific mortality accumulates slowly with increasing follow-up. ⋯ Systematic PSA-based screening reduced PCa-specific mortality by 32% in the age range of 55-69 yr. The roughly twofold higher incidence in the S-arm underlines the importance of tools to better identify those men who would benefit from screening.