Addictive behaviors
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Addictive behaviors · Apr 2020
Adolescent E-cigarette use trajectories and subsequent alcohol and marijuana use.
As electronic cigarette (e-cigarette) use has become more prevalent among adolescents, there is a growing body of evidence linking e-cigarette use to the initiation of other substances. Whether there is a threshold level of e-cigarette use that is predictive of other substance use is unknown. The current study examines patterns of e-cigarette use over time and determines whether different patterns of early adolescent e-cigarette use are concurrently and prospectively associated with alcohol and marijuana use in late adolescence. ⋯ Both high and low levels of e-cigarette use patterns are associated with increasing use of other substances (alcohol and marijuana use) over time. Findings highlight the need for early intervention and prevention of e-cigarette use among adolescents.
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Addictive behaviors · Mar 2020
Childhood adversity and mental health comorbidity in men and women with opioid use disorders.
To examine gender differences in associations between mental health comorbidity and adverse childhood experiences (ACE) among adults with DSM-5 lifetime opioid use disorders (OUD). ⋯ Among adults with OUD, ACE alters the gender gap in risk for comorbid mood or anxiety disorders. Using gender-tailored methods to address the harmful effects ACE on the mental health of individuals with OUD may help to prevent and ameliorate the current opioid epidemic.
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Addictive behaviors · Mar 2020
Data sharing practices in randomized trials of addiction interventions.
Transparent, open scientific research practices aim to improve the validity and reproducibility of research findings. A key component of open science is the public sharing of data and metadata that constitute the basis for research findings. ⋯ Our finding has significant implications for the addiction research community. These implications are broad, ranging from possibly slowed scientific advancement to noncompliance with obligations to the public whose tax dollars funded a large majority of the included RCTs. To improve the rates of data sharing, we recommend studying incentive systems, while simultaneously working to cultivate a data sharing system that emphasizes scientific, rather than author, accuracy.
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Addictive behaviors · Mar 2020
Organizational factors associated with practitioners' support for treatment of opioid use disorder in the emergency department.
Despite the significant increase in emergency room visits for opioid overdose, only few emergency departments (ED) have implemented best practices to treat people with opioid use disorders (OUD). Some implementation gaps may be due to practitioner factors; such as support for medication-assisted treatment (MAT) for OUD in the ED. In this study, we explore the relationship between inner setting characteristics of the EDs (e.g., leadership, readiness for change, organizational climate) and practitioner support for OUD treatment and attitudes towards people with OUD. ⋯ Findings suggest that professional roles and some ED inner setting factors play an important role in antecedents of implementation of OUD treatment in the ED. To prepare EDs to effectively respond to the current opioid overdose epidemic, it is critical to further understand the impact of these organizational factors on the implementation of evidence-based OUD treatment practices in the nation.
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Addictive behaviors · Mar 2020
Sex differences in the relationship between anxiety sensitivity and opioid misuse among adults with chronic pain.
The opioid epidemic is a significant public health concern linked to chronic pain. Despite efforts to change opioid prescribing practices for chronic pain, opioid-involved overdoses remain at an all-time high. Research focused on identifying individual difference factors for problematic opioid misuse in the context of chronic pain have identified certain psychological variables that may confer heightened risk for opioid-related problems. ⋯ Results indicated that the relation between anxiety sensitivity and current opioid misuse (ΔR2 = 0.005, B = 0.12, SE = 0.06, p = 0.04), and opioid dependence (ΔR2 = 0.01, B = 0.04, SE = 0.02, p = 0.007) was stronger for males compared to females. These results suggest that anxiety sensitivity may be associated with opioid-related problems to a greater extent for males than females. Continued research is needed to examine how these sex differences may impact clinical treatment for opioid-related problems.