The New England journal of medicine
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Whether higher levels of physical activity can counteract the elevated risk of death associated with adiposity is controversial. ⋯ Both increased adiposity and reduced physical activity are strong and independent predictors of death.
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Multicenter Study Comparative Study
Maternal and perinatal outcomes associated with a trial of labor after prior cesarean delivery.
The proportion of women who attempt vaginal delivery after prior cesarean delivery has decreased largely because of concern about safety. The absolute and relative risks associated with a trial of labor in women with a history of cesarean delivery, as compared with elective repeated cesarean delivery without labor, are uncertain. ⋯ A trial of labor after prior cesarean delivery is associated with a greater perinatal risk than is elective repeated cesarean delivery without labor, although absolute risks are low. This information is relevant for counseling women about their choices after a cesarean section.
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Randomized Controlled Trial Multicenter Study Comparative Study Clinical Trial
Palifermin for oral mucositis after intensive therapy for hematologic cancers.
Oral mucositis is a complication of intensive chemotherapy and radiotherapy with no effective treatment. We tested the ability of palifermin (recombinant human keratinocyte growth factor) to decrease oral mucosal injury induced by cytotoxic therapy. ⋯ Palifermin reduced the duration and severity of oral mucositis after intensive chemotherapy and radiotherapy for hematologic cancers.