The New England journal of medicine
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Randomized Controlled Trial Clinical Trial
Zinc supplementation in young children with acute diarrhea in India.
In developing countries the duration and severity of diarrheal illnesses are greatest among infants and young children with malnutrition and impaired immune status, both factors that may be associated with zinc deficiency. In children with severe zinc deficiency, diarrhea is common and responds quickly to zinc supplementation. ⋯ For infants and young children with acute diarrhea, zinc supplementation results in clinically important reductions in the duration and severity of diarrhea.
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Randomized Controlled Trial Multicenter Study Comparative Study Clinical Trial
Noninvasive ventilation for acute exacerbations of chronic obstructive pulmonary disease.
In patients with acute exacerbations of chronic obstructive pulmonary disease, noninvasive ventilation may be used in an attempt to avoid endotracheal intubation and complications associated with mechanical ventilation. ⋯ In selected patients with acute exacerbations of chronic obstructive pulmonary disease, noninvasive ventilation can reduce the need for endotracheal intubation, the length of the hospital stay, and the in-hospital mortality rate.