The New England journal of medicine
The most recent articles from:
N. Engl. J. Med.
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Comment Letter Case Reports
A simpler technique for umbilical-cord blockade of an acardiac twin.
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Letter Case Reports
Treatment of cutaneous T-cell lymphoma with beta carotene.
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Although effective treatments for hyperthyroidism are available, none is perfect. Particularly with respect to Graves' disease, what is needed is a therapy directed at modulating the disease process itself rather than merely reducing the synthesis and secretion of thyroid hormones in the hope that the underlying Graves' disease will remit. ⋯ Broad-spectrum immunosuppression, with all its side effects, is not the answer; more focused therapies to inhibit the immune response to specific thyroid antigens may represent the treatment of the future. Meanwhile, radioiodine therapy is the most effective and convenient method of achieving long-term control of hyperthyroidism, although at the cost of hypothyroidism in many patients.