The New England journal of medicine
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Randomized Controlled Trial Clinical Trial
Effect of acetazolamide on hypoxemia during sleep at high altitude.
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Randomized Controlled Trial Clinical Trial
A controlled study of short-term prednisone treatment in adults with membranous nephropathy.
Seventy-two adults with the nephrotic syndrome without renal insufficiency had a membranous type of renal histology on biopsy. These patients were randomly allocated to at least eight weeks of alternate-day treatment with prednisone or placebo in a multicenter study. ⋯ Age, admission blood pressure, serum creatinine, daily total protein excretion, and severity of histologic changes did not predict the subsequent course. We conclude that a short course of alternate-day prednisone therapy was beneficial in our group of patients with idiopathic membranous nephropathy.