The New England journal of medicine
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Historical Article
In whose best interest? Breaching the academic-industrial wall.
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Randomized Controlled Trial Clinical Trial
Intrathecal methylprednisolone for intractable postherpetic neuralgia.
There is no effective treatment for intractable postherpetic neuralgia. Because there is evidence that postherpetic neuralgia has an inflammatory component, we assessed treatment with intrathecally administered methylprednisolone to reduce pain in patients with this disorder. ⋯ The results of this trial indicate that the intrathecal administration of methylprednisolone is an effective treatment for postherpetic neuralgia.