The New England journal of medicine
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Multicenter Study
Effect of left ventricular outflow tract obstruction on clinical outcome in hypertrophic cardiomyopathy.
The influence of left ventricular outflow tract obstruction on the clinical outcome of hypertrophic cardiomyopathy remains unresolved. ⋯ In patients with hypertrophic cardiomyopathy, left ventricular outflow tract obstruction at rest is a strong, independent predictor of progression to severe symptoms of heart failure and of death.