The New England journal of medicine
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Randomized Controlled Trial Comparative Study
Weight loss with a low-carbohydrate, Mediterranean, or low-fat diet.
Trials comparing the effectiveness and safety of weight-loss diets are frequently limited by short follow-up times and high dropout rates. ⋯ Mediterranean and low-carbohydrate diets may be effective alternatives to low-fat diets. The more favorable effects on lipids (with the low-carbohydrate diet) and on glycemic control (with the Mediterranean diet) suggest that personal preferences and metabolic considerations might inform individualized tailoring of dietary interventions. (ClinicalTrials.gov number, NCT00160108.)