The New England journal of medicine
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Comment Letter
Early or late parenteral nutrition in critically ill adults.
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Multicenter Study Clinical Trial
Early liver transplantation for severe alcoholic hepatitis.
A 6-month abstinence from alcohol is usually required before patients with severe alcoholic hepatitis are considered for liver transplantation. Patients whose hepatitis is not responding to medical therapy have a 6-month survival rate of approximately 30%. Since most alcoholic hepatitis deaths occur within 2 months, early liver transplantation is attractive but controversial. ⋯ Early liver transplantation can improve survival in patients with a first episode of severe alcoholic hepatitis not responding to medical therapy. (Funded by Société Nationale Française de Gastroentérologie.).