The New England journal of medicine
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Randomized Controlled Trial
Long-term mortality after screening for colorectal cancer.
In randomized trials, fecal occult-blood testing reduces mortality from colorectal cancer. However, the duration of the benefit is unknown, as are the effects specific to age and sex. ⋯ The effect of screening with fecal occult-blood testing on colorectal-cancer mortality persists after 30 years but does not influence all-cause mortality. The sustained reduction in colorectal-cancer mortality supports the effect of polypectomy. (Funded by the Veterans Affairs Merit Review Award Program and others.).
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Comment Letter
Oncofetal gene SALL4 in aggressive hepatocellular carcinoma.