The New England journal of medicine
-
Comment Letter
Intensity-modulated radiation therapy for prostate cancer.
-
Randomized Controlled Trial Multicenter Study Comparative Study
Comparison of pregabalin with pramipexole for restless legs syndrome.
Dopaminergic medications relieve symptoms of the restless legs syndrome (RLS) but have the potential to cause iatrogenic worsening (augmentation) of RLS with long-term treatment. Pregabalin may be an effective alternative. ⋯ Pregabalin provided significantly improved treatment outcomes as compared with placebo, and augmentation rates were significantly lower with pregabalin than with 0.5 mg of pramipexole. (Funded by Pfizer; ClinicalTrials.gov number, NCT00806026.).