The New England journal of medicine
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Comment Letter
Sitagliptin and Cardiovascular Outcomes in Type 2 Diabetes.
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Randomized Controlled Trial
Endobronchial Valves for Emphysema without Interlobar Collateral Ventilation.
Bronchoscopic lung-volume reduction with the use of one-way endobronchial valves is a potential treatment for patients with severe emphysema. To date, the benefits have been modest but have been hypothesized to be much larger in patients without interlobar collateral ventilation than in those with collateral ventilation. ⋯ Endobronchial-valve treatment significantly improved pulmonary function and exercise capacity in patients with severe emphysema characterized by an absence of interlobar collateral ventilation. (Funded by the Netherlands Organization for Health Research and Development and the University Medical Center Groningen; Netherlands Trial Register number, NTR2876.).