The New England journal of medicine
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Randomized Controlled Trial Multicenter Study Comparative Study
Less-tight versus tight control of hypertension in pregnancy.
The effects of less-tight versus tight control of hypertension on pregnancy complications are unclear. ⋯ We found no significant between-group differences in the risk of pregnancy loss, high-level neonatal care, or overall maternal complications, although less-tight control was associated with a significantly higher frequency of severe maternal hypertension. (Funded by the Canadian Institutes of Health Research; CHIPS Current Controlled Trials number, ISRCTN71416914; ClinicalTrials.gov number, NCT01192412.).