The New England journal of medicine
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Randomized Controlled Trial Multicenter Study
Perioperative Bridging Anticoagulation in Patients with Atrial Fibrillation.
In patients with atrial fibrillation requiring cessation of warfarin for surgery, bridging anticoagulation does not change the incidence of thromboembolism, although does increase major bleeding.
pearl -
Sleep loss in attending physicians has an unclear effect on patient outcomes. In this study, we examined the effect of medical care provided by physicians after midnight on the outcomes of their scheduled elective procedures performed during the day. ⋯ Overall, the risks of adverse outcomes of elective daytime procedures were similar whether or not the physician had provided medical services the previous night. (Funded by the University of Toronto Dean's Fund and others.).