The New England journal of medicine
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Editorial Comment
Major Strides in HER2 Blockade for Metastatic Breast Cancer.
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Randomized Controlled Trial Multicenter Study Comparative Study
Lower versus Traditional Treatment Threshold for Neonatal Hypoglycemia.
Worldwide, many newborns who are preterm, small or large for gestational age, or born to mothers with diabetes are screened for hypoglycemia, with a goal of preventing brain injury. However, there is no consensus on a treatment threshold that is safe but also avoids overtreatment. ⋯ In otherwise healthy newborns with asymptomatic moderate hypoglycemia, a lower glucose treatment threshold (36 mg per deciliter) was noninferior to a traditional threshold (47 mg per deciliter) with regard to psychomotor development at 18 months. (Funded by the Netherlands Organization for Health Research and Development; HypoEXIT Current Controlled Trials number, ISRCTN79705768.).