International journal of radiation oncology, biology, physics
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Int. J. Radiat. Oncol. Biol. Phys. · Aug 1994
Clinical TrialDownstaging of advanced rectal cancer following combined preoperative chemotherapy and high dose radiation.
To assess the potential downstaging of advanced rectal cancer with combined preoperative chemoradiation. ⋯ Concomitant preoperative chemoradiation using low dose continuous infusional 5-FU for advanced rectal cancer is relatively safe with acceptable morbidity. This approach is associated with considerable clinical and pathologic downstaging of cancer. Tumor resectability is improved with potential for improved local control of disease and survival.
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Int. J. Radiat. Oncol. Biol. Phys. · Aug 1994
Editorial Comment Comparative StudyThe relationship between local relapse and distant metastases revisited.